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September/October 2014 Sept/Oct 2014

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Nonwovens / Technical Textiles

Xanofi Introduces XanoMatrix™ 3-D Cell Scaffold

Xanofi, a Raleigh, N.C.-based advanced nanomaterials manufacturer, has launched its next-generation 3-D cell culturing products under the XanoMatrix™ brand.
 
The short staple nanofibers in XanoMatrix scaffolds enable creation of a highly porous, evenly spread structure that cells can penetrate and remodel, according to Xanofi. The company reports the nanofibers have been used successfully in experiments to grow stem cells as well as a range of cancer cells and primary cells. Potential cell growth applications include fixed bed reactors, regenerative medicine, laboratory plate culturing, in vitro cancer work and other applications. It also can be sprayed through 3-D printers or shaped into specific forms. RNA/DNA analysis, cell viability/proliferation, fluorescent microscopy, cryosectioning and protein extraction can be conducted with little change, if any, in current protocols. Complex co-culturing and complete multiple cell type tissue modeling are also possible, Xanofi reports.
 
“The key to XanoMatrix is the use of short, staple nanofibers that allow cells to remodel the scaffold while establishing dynamic nutrient gradients,” said Xanofi CEO Miles Wright. “It’s probably the closest biomimic to ECM on the market and can be customized to provide solutions in several key areas of tissue engineering.”
 
July 1, 2014
 




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